States › South Carolina › Greenville County › ZIP 29681
ZIP Code Tabulation Area · South Carolina
ZIP Code 29681
63,257 residents in the 2020 Census, 47,002 adults. Spans 2 counties; CDC PLACES 2025 release.
- Greenville County · 97.5% of land
- Laurens County · 2.5% of land
- Five Forks CDP · 17% of land
- Simpsonville city · 13% of land
- Mauldin city · 3% of land
ZIP Code 29681, mainly in Greenville County, South Carolina, has 63,257 residents in the 2020 Census (47,002 adults). CDC's PLACES project estimates 40 health measures for its adult population using a statistical model, not a local survey.
In the 2025 release it estimates that 30.2% of adults have obesity (95% confidence interval 26.2–34.3%), similar to Greenville County's 32.5%, below the South Carolina figure of 35.8% (site aggregate), similar to the national estimate of 32.8%. Where intervals overlap the figures are described as similar, because the model cannot separate them.
Diagnosed diabetes: 10.7% of adults (95% confidence interval 9.4–12.0%) in the 2025 release, similar to Greenville County's 12.2%, below the South Carolina figure of 13.9% (site aggregate), similar to the national estimate of 12.0%.
Across the 40 measures published for both, the interval for ZIP Code 29681 lies entirely above the Greenville County interval for 0 measures, entirely below it for 4 and overlaps it for 36.
Report card: 40 measures by CDC category
Crude prevalence is the estimated share of all adults. CDC: "We don't provide age-adjusted prevalence estimates at census tract and ZCTA levels because some of these areas do not have population in all age groups used in the adjustment process."
estimate with 95% intervalGreenville Co.SC figureUS estimate
Health outcomes (12)vs Greenville Co.: 0 higher · 1 lower · 11 similar
Prevention (7)vs Greenville Co.: 0 higher · 0 lower · 7 similar
Health risk behaviors (4)vs Greenville Co.: 0 higher · 0 lower · 4 similar
Disability (7)vs Greenville Co.: 0 higher · 1 lower · 6 similar
Health status (3)vs Greenville Co.: 0 higher · 0 lower · 3 similar
Health-related social needs (7)vs Greenville Co.: 0 higher · 2 lower · 5 similar
Flags: Co. = Greenville County, St. = South Carolina figure (site aggregate, no interval: above, below or in line), US = national estimate. ↑ interval entirely above, ↓ entirely below, ≈ overlapping or containing the reference. Hover a flag for the wording. Release column in colour: not published for this ZIP in the 2025 release, most recent published release shown.
Compared with county, state and nation
| Measure | This ZIP | Greenville County | South Carolina (site aggregate) | United States |
|---|---|---|---|---|
| Obesity | 30.2% 26.2–34.3 | 32.5% 28.1–37.0 · similar | 35.8% below | 32.8% 32.4–33.1 · similar |
| Diabetes | 10.7% 9.4–12.0 | 12.2% 10.6–14.0 · similar | 13.9% below | 12.0% 11.8–12.2 · similar |
| High Blood Pressure | 33.7% 30.9–36.7 | 35.6% 32.5–38.8 · similar | 38.5% below | 34.4% 34.0–34.7 · similar |
| Current Asthma | 9.1% 8.1–10.1 | 9.4% 8.4–10.7 · similar | 9.6% in line | 9.8% 9.6–10.0 · similar |
| COPD | 5.2% 4.7–5.8 | 6.4% 5.2–7.8 · similar | 7.5% below | 6.2% 6.1–6.3 · lower |
| Coronary Heart Disease | 5.3% 4.8–5.9 | 6.1% 5.3–7.0 · similar | 6.8% below | 6.4% 6.2–6.5 · lower |
| Depression | 21.2% 18.6–23.8 | 21.8% 19.1–24.7 · similar | 22.3% in line | 20.2% 19.9–20.5 · similar |
| Current Cigarette Smoking | 9.3% 8.0–10.5 | 11.3% 9.0–14.1 · similar | 13.3% below | 11.4% 11.2–11.6 · lower |
| Binge Drinking | 16.3% 14.0–18.8 | 15.6% 13.3–18.2 · similar | 15.7% in line | 15.2% 15.0–15.5 · similar |
| Physical Inactivity | 19.1% 16.7–21.6 | 23.2% 19.7–27.3 · similar | 25.8% below | 24.5% 24.2–24.8 · lower |
| Health Insurance | 8.2% 7.2–9.3 | 11.4% 9.2–14.0 · similar | 11.8% below | 11.0% 10.7–11.3 · lower |
| General Health | 13.9% 12.4–15.5 | 17.5% 14.8–20.7 · similar | 20.1% below | 19.2% 18.9–19.5 · lower |
Twelve headline measures, crude prevalence. State figures are population-weighted county estimates computed by this site and carry no interval; the county and US columns carry CDC's 95% intervals. The full report card above covers all 40.
Estimates by release
What each PLACES release published for ZIP 29681 (crude prevalence with 95% interval). CDC advises that the estimates cannot be used to track local change over time: each release re-models a different survey year onto a fixed population, intervals usually overlap and the interval method changed in 2023. Listed for reference only. The 2022 and 2023 columns use 2010-vintage Census geographies for ZIP Codes and places (the same code may have covered a different area); 2024 onward use 2020 geographies.
| Measure | 2022 release | 2023 release | 2024 release | 2025 release |
|---|---|---|---|---|
| COPD | 4.9% 4.6–5.2 | 4.8% 4.2–5.4 | 5.3% 4.7–5.8 | 5.2% 4.7–5.8 |
| Coronary Heart Disease | 4.9% 4.7–5.1 | 4.4% 3.9–4.9 | 5.6% 5.0–6.1 | 5.3% 4.8–5.9 |
| Current Asthma | 9.1% 8.9–9.2 | 8.4% 7.5–9.5 | 8.8% 7.8–9.9 | 9.1% 8.1–10.1 |
| Depression | 21.3% 20.9–21.7 | 19.5% 16.9–22.3 | 21.8% 19.1–24.6 | 21.2% 18.6–23.8 |
| Diabetes | 8.5% 8.3–8.8 | 8.3% 7.2–9.4 | 9.5% 8.3–10.7 | 10.7% 9.4–12.0 |
| High Blood Pressure | 28.4% 28.0–28.8 | 29.9% 27.0–32.8 | 32.5% 29.5–35.7 | 33.7% 30.9–36.7 |
| Obesity | 30.3% 29.8–30.7 | 31.1% 27.0–35.3 | 29.0% 25.0–33.1 | 30.2% 26.2–34.3 |
| Health Insurance | 11.8% 11.1–12.6 | 8.7% 7.6–10.0 | 8.9% 7.8–10.0 | 8.2% 7.2–9.3 |
| Binge Drinking | 19.1% 18.9–19.4 | 17.7% 15.1–20.6 | 18.1% 15.3–20.9 | 16.3% 14.0–18.8 |
| Current Cigarette Smoking | 14.1% 13.2–14.9 | 12.3% 10.5–14.3 | 11.0% 9.7–12.4 | 9.3% 8.0–10.5 |
| Physical Inactivity | 18.3% 17.6–19.0 | 18.7% 16.3–21.3 | 19.0% 16.6–21.6 | 19.1% 16.7–21.6 |
| General Health | 10.3% 9.8–10.9 | 11.1% 9.8–12.4 | 11.9% 10.7–13.3 | 13.9% 12.4–15.5 |
Nearby
All 23 ZIP Codes in Greenville County and its 24 places · South Carolina (420 ZIP Codes).
Questions and answers
What share of adults in ZIP Code 29681 have obesity, according to PLACES?
PLACES estimates 30.2% (95% confidence interval 26.2–34.3%) in the 2025 release, based on 2023 BRFSS responses modelled onto the area's adult population. It is a modelled estimate for the whole adult population of the area, not a count of diagnoses.
How common is diagnosed diabetes in ZIP Code 29681?
PLACES estimates 10.7% of adults (95% confidence interval 9.4–12.0%) in the 2025 release. The national estimate in the same release is 12.0%.
Is ZIP Code 29681 different from Greenville County on obesity?
The 95% confidence intervals for ZIP Code 29681 and Greenville County overlap for obesity, so the estimates are described as similar; the model cannot separate them.
Can these figures describe a person who lives in ZIP Code 29681?
No. CDC states: "We do not produce estimates for individuals; only aggregated results for counties, places, census tracts, or ZCTAs." The figures describe the expected prevalence across the area's adult population given its demographic make-up and its county and state; they say nothing about any resident.
Can ZIP Code 29681 be ranked or tracked over time with these figures?
CDC advises that the data "should not be used for ranking the overall health of any county, place, census tract, or ZCTA" and that the modelling procedure "does not support using the estimates to track changes at the local level over time". Areas can be compared on individual measures, with their confidence intervals; this site lists estimates by release for reference only.
Where does this data come from?
CDC PLACES: Local Data for Better Health, 2025 release (data updated 4 Dec 2025), which models Behavioral Risk Factor Surveillance System responses with Census population and American Community Survey data. Earlier releases (2022, 2023, 2024) are shown for reference. Boundaries and ZIP-to-county relationships are from the US Census Bureau.
Provenance
Source: Centers for Disease Control and Prevention, PLACES: Local Data for Better Health, 2025 release (data updated 4 Dec 2025), with the 2022, 2023, 2024 releases for reference; US government work, public domain. Dataset on data.cdc.gov. Boundaries and ZIP-to-county relationships: US Census Bureau. Percentages are shown to one decimal as CDC publishes them; state figures are population-weighted means computed by this site. ZCTA-to-county and ZCTA-to-place shares are land-area overlaps from the Census 2020 relationship files. PLACES does not publish age-adjusted figures for ZCTAs. Processing errors are corrected at the next daily build; see corrections. Generated 1 Oct 2026.